Phospho stat5
WebSee all STAT5 primary antibodies Description Rabbit monoclonal [E208] to STAT5 (phospho Y694) Host species Rabbit Tested applications Suitable for: WB, IHC-P, ELISA more … WebDescription. STAT5 is a member of the signal transducer and activator of transcription factors (STAT) family, mediating growth and cytokine signaling. STAT5 consists of two …
Phospho stat5
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WebJun 20, 2013 · GM-CSF-dependent pSTAT5 sensitivity is a feature with therapeutic potential in chronic myelomonocytic leukemia Granulocyte-macrophage-colony-stimulating factor (GM-CSF) hypersensitivity is a hallmark of juvenile myelomonocytic leukemia (JMML) but has not been systematically shown in the related human disease chronic myelomonocytic … WebThis Phospho-Cell-Based ELISA Kit employs fluorometric detection that is compatible with standard microplate fluorometers. PRODUCT FEATURES ... (STAT5) is a member of the …
WebJul 1, 2007 · STAT5 is generally activated by one of the 3 mechanisms: (1) by Jak kinases, (2) by Src family kinases (SFK), or (3) directly by RTKs such as the EGFR, PDGFRB, or insulin receptors. 14, 15 Although phosphorylation of Jak2 or Tyk2 by Flt3-ITD has been shown in previous studies, the role of Jak kinases in Flt3-ITD signaling remains controversial … WebThis Phospho-Cell-Based ELISA Kit employs fluorometric detection that is compatible with standard microplate fluorometers. PRODUCT FEATURES ... (STAT5) is a member of the Jak/STAT signal transduction pathway and is activated by a variety of cytokines (IL22, IL6, IFN-α). STAT5 has two isoforms (A and B) that share 93% amino acid identity and ...
WebNov 15, 2013 · In order to validate a phospho-specific flow cytometry assay assessing phospho-signal transducer and activator of transcription factor 5 (p-STAT5) as a new diagnostic tool for JMML, we examined 22 samples from children with JMML and 47 controls. ... In conclusion, flow cytometric p-STAT5 profiling is a reliable diagnostic tool … WebStat5 is constitutively active in some leukemic cell types (4). Phosphorylated Stat5 is found in some endothelial cells treated with IL-3, which suggests its involvement in …
WebInvitrogen Anti-Phospho-STAT5 alpha (Ser780) Polyclonal, Catalog # PA5-36891. Tested in Western Blot (WB) and Immunohistochemistry (Paraffin) (IHC (P)) applications. This …
WebSTAT5 alpha is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. black and missing foundation foundersWebSTAT5 is phosphorylated by several JAKs, including Jak3, Jak2, and Tyk2, in response to interleukin-2, erythropoietin (EPO), and interleukin-22, respectively. Activation of STAT5 is essential to T cell development and has been associated with hematologic malignancies. black and missing cold casesWebMay 31, 2024 · p-Stat5a/b Antibody (5G4) is an IgG 1 mouse monoclonal p-Stat5a/b antibody suitable for the detection of Tyr 694 phosphorylated Stat5a and Tyr 699 phosphorylated Stat5b of mouse, rat and human origin by WB, IP and IF. p-Stat5a/b Antibody (5G4) is available as the non-conjugated anti-p-Stat5a/b antibody form. Stat5 (Signal … black and missing incWebSee all STAT5 primary antibodies Description Rabbit polyclonal to STAT5 (phospho Y694) Host species Rabbit Tested applications Suitable for: WB, ICC/IF more details Species reactivity Reacts with: Human Predicted to work with: Mouse, Rat, Sheep, Cow, Pig Immunogen Synthetic peptide. This information is proprietary to Abcam and/or its suppliers. black and missing hboWebThe signal transducer and activator of transcription-5 (STAT5) protein has been shown to play an important role in tumor progression through stimulating cell proliferation and … black and missing foundation incWeb人抗胰蛋白酶(at)elisa试剂盒 ；英文名称： at elisa kit ；实验名称： 人抗胰蛋白酶(at)elisa试剂盒 ；实验别名： 人抗胰蛋白酶(at)elisa试剂盒 48t/96t ；规格： 48t/96t 报价 人抗胰蛋白酶(at)elisa试剂盒实验目的：本试剂盒仅供研究使用 ，用于 用于测定血清、血浆及相关液体样本中待测物质的含量 。 black and missing websiteWebSTAT5 antibodies are immunological tools used to detect two very closely related proteins known collectively as signal transducer and activator of transcription 5. The two proteins are encoded by the genes STAT5A and STAT5B. STAT5 is involved in signal transduction and mediation of gene expression as a transcription factor. black and missing organization